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How can I reduce the side effects of capecitabine?

How can I reduce the side effects of capecitabine?

Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Diarrhea is a common side effect of this medication. Drink plenty of fluids unless directed otherwise.

Does capecitabine cause hyperpigmentation?

Capecitabine has several side effects, most common of which is Hand-Foot syndrome (HFS); however, less frequently reported is capecitabine-associated hyperpigmentation.

Do you lose your hair with capecitabine?

When used on its own, capecitabine occasionally causes some temporary hair thinning. It very rarely causes complete hair loss. If capecitabine is taken in combination with another chemotherapy drug, most people will lose all their hair including eyebrows, eyelashes and body hair.

Does capecitabine cause rashes?

Common adverse reactions to capecitabine include diarrhea and nausea, fatigue and elevated bilirubin, and hand-and-foot syndrome. Other rashes are rare [3].

When should I stop taking capecitabine?

Your doctor may tell you to stop taking XELODA if you have a serious skin reaction. Do not take XELODA again if this happens. in sensation in your hands and feet, or cause redness, pain, swelling of your hands and feet.

What is the best lotion for hand foot syndrome?

Emollients such as Aveeno®, Lubriderm®, Udder Cream®, and Bag Balm® provide excellent moisturizing to your hands and feet.

Why would skin turn black?

If your body makes too much melanin, your skin gets darker. Pregnancy, Addison’s disease, and sun exposure all can make your skin darker.

How long is capecitabine effective?

A prespecified interim analysis showed that the study had met its primary endpoint and was thus terminated early, after a median follow-up of 3.6 years. At 3 years, 82.8% of capecitabine patients were alive and free from recurrence or second cancer, compared with 73.9% of control patients.

Is there an alternative to capecitabine?

Possible alternative treatment options to be considered are to replace the oral capecitabine or intravenous 5-FU by a 5-FU bolus regimen, by uracil-tegafur or tegafur/gimeracil/oteracil, both oral fluoropyrimidines combining a 5-FU prodrug with a dihydropyrimidine dehydrogenase (DPD) inhibitor, or by raltitrexed, a …

How can I regain my original skin color?

  1. Exfoliate regularly with a gentle scrub.
  2. Moisturise well.
  3. Eat foods rich in antioxidants like Vitamin C, daily.
  4. Use a sunscreen (with SPF 30 and PA+++) every day, without fail.
  5. Use a skin brightening face pack if you have an uneven skin tone.
  6. Get a facial done at your salon every 20 to 30 days.

Are there any side effects to taking capecitabine?

Capecitabine side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Diarrhea may occur and could be severe.

When to stop taking capecitabine for skin cancer?

Stop taking capecitabine and call your cancer doctor if the skin reaction is painful, as your dose may need to be changed. Taking a lower dose does not affect the usefulness of capecitabine. Nausea and vomitingmay occur while you are taking capecitabine. Many people have little or no nausea.

What to do with dry skin from capecitabine?

Skin may also become dry or itchy. You may not be able to do your normal daily activities if blisters, severe pain or ulcers occur. •Avoid tight fitting shoes or rubbing caused by heavy activity. • Clean hands and feet with lukewarm water and gently pat to dry; avoid hot water.

What are the precautionary steps for capecitabine?

Precautions. Check with your doctor right away if you have blistering, peeling, or loose skin, red skin lesions, pain, swelling, or blisters on the palms of your hands or soles of your feet, loss of fingerprints, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.