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What is multicentric tumor?

What is multicentric tumor?

Multicentric: Having more than one center. A term often applied to tumors. A minority of Wilms tumors are multicentric and appear to represent separate tumors. A multicentric breast cancer involves two or more distinct primary tumors, usually in different quadrants of the breast. Also called multifocal or polycentric.

What is multifocal and multicentric cancer?

Breast cancers are defined as multifocal when there is more than one distinct tumour within the same quadrant of the breast (MF) and multicentric when multiple cancers develop in different quadrants of the breast (MC) [5].

What is tumor Multifocality?

Multifocal breast cancer occurs when there are two or more tumors in the same breast. All of the tumors begin in one original tumor. The tumors are also all in the same quadrant — or section — of the breast. Multicentric breast cancer is a similar type of cancer.

How is multicentric breast cancer staged?

A mammogram will use X-rays to detect changes in the breast. An MRI uses powerful magnets and radio waves to create detailed images the breast’s inner tissues. This particular imaging test is the most accurate at finding multifocal breast cancers. An ultrasound provides detailed images in real-time.

What is Wilms tumor?

Wilms tumor (also called Wilms’ tumor or nephroblastoma) is a type of childhood cancer that starts in the kidneys. It is the most common type of kidney cancer in children. About 9 of 10 kidney cancers in children are Wilms tumors. Cancer starts when cells in the body begin to grow out of control.

What does unifocal tumor mean?

Unifocal refers to the primary tumour having a single foci of cancer cells, and multifocal refers to the primary tumour having two or more foci of cancer cells. Definitions of focality in relation to spread are specific to the cancer site.

What is multicentric disease?

A multicentric breast cancer is a term given to a breast cancer where there are two or more breast cancers separated by normal breast tissue (often taken as 5 cm of separation 4). It is related to but distinct from the term multifocal breast cancer.

What is the treatment for multifocal breast cancer?

There are several treatment options available for multifocal breast cancer. These include lumpectomy, mastectomy, radiation therapy, hormonal therapy, and chemotherapy.

What are sentinel lymph nodes?

A sentinel lymph node is defined as the first lymph node to which cancer cells are most likely to spread from a primary tumor. Sometimes, there can be more than one sentinel lymph node.

How common is multicentric breast cancer?

Introduction. Multifocal and multicentric breast cancer (MMBC) is common, with a reported incidence of 9–75%. Incidence varies according to the extent of breast tissue sampling, but this wide range of reported incidence also reflects the lack of a standard definition of MMBC.

Is Wilms tumor fatal?

Wilms tumor is a rare kidney cancer that is highly treatable. Most kids with Wilms tumor survive and go on to live normal, healthy lives. Also known as nephroblastoma, Wilms tumor can affect both kidneys, but usually develops in just one.

Is Wilms tumor aggressive?

But they soon found out her symptoms were caused by something much worse: a Wilms tumor (a type of kidney tumor) with diffuse anaplasia (this means cells that are aggressive and resistant to treatment). This is the rarest type of Wilms tumor and the most challenging to overcome.

What does multicentric breast cancer mean in medical terms?

multicentric breast cancer. listen (MUL-tee-SEN-trik brest KAN-ser) Breast cancer in which there is more than one tumor, all of which have formed separately from one another. The tumors are likely to be in different quadrants (sections) of the breast.

What is the importance of multifocal / multicentric tumor?

The importance of multifocal/multicentric tumor on the disease-free survival of breast cancer patients: single center experience M/M imparts an unfavorable prognosis on the DFS of breast cancer patients in comparison to unifocal tumors and the presence of multifocal/multicentric tumors were associated with advanced pT and pN stages.

What do you call a tumor with more than one center?

Multicentric: Having more than one center. A term often applied to tumors. A minority of Wilms tumors are multicentric and appear to represent separate tumors. A multicentric breast cancer involves two or more distinct primary tumors, usually in different quadrants of the breast. Also called multifocal or polycentric.

What is the definition of multifocal breast cancer?

Multicentric and multifocal breast cancer were defined as the presence of 2 or more invasive tumor foci within the different quadrants of the same breast or within a same quadrant of the breast, respectively. M/M and other prognostic factors were evaluated using univariate and multivariate analyses.