How bad is acinic cell carcinoma?
Acinic cell carcinoma (AciCC) of salivary gland is a relatively infrequent tumor. Though known for its low-grade behavior, its unpredictable element of recurrence and malignancy should never be ignored.
Can acinic cell carcinoma spread?
Although acinic cell carcinomas rarely metastasize, they have a high tendency to recur locally if they are incompletely excised. We describe a patient with acinic cell tumor arising in the parotid gland, with metastases to the contralateral orbit, submandibular salivary gland, and submandibular lymph node.
What causes acinic cell carcinoma?
Acinic cell carcinoma is more prevalent in women than in men. The exact cause of salivary gland cancers, including acinic cell carcinoma, is unknown; however, research suggests that possible causes of the disease may be previous exposure to radiation, wood dust inhalation, and a family history of salivary cancers.
Is acinic cell carcinoma hereditary?
The histologic features of both neoplasms were typical of acinic cell carcinoma. While this may represent a coincidental event, the possibility that this familial occurrence is a manifestation of common genetic or environmental risk cannot be excluded.
Can acinic cell carcinoma be cured?
The 10-year cumulative survival rate was 90.9% with a mean follow-up of 111 months, ranging 17-251 months. The 10-year disease free survival rate was 74.2% and the mean duration of recurrence from initial surgery was 92.3 months (Fig. 1). 10-year disease free survival of parotid acinic cell carcinoma patients.
What is the meaning of clear cell carcinoma?
Listen to pronunciation. (kleer sel KAR-sih-NOH-muh) A rare type of tumor, usually of the female genital tract, in which the insides of the cells look clear when viewed under a microscope. Also called clear cell adenocarcinoma and mesonephroma.
What is warthin’s tumor?
Warthin tumor is a benign tumor of the salivary gland. The first symptom is usually a painless, slow-growing bump in front of the ear, on the bottom of the mouth, or under the chin. Warthin tumors may increase in size over time, but few become cancerous.
What is acinic cell carcinoma?
Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.
What is the most common parotid tumor?
Mucoepidermoid carcinomas are the most common type of salivary gland cancer. Most start in the parotid glands. They develop less often in the submandibular glands or in minor salivary glands inside the mouth.
What happens when the parotid gland is removed?
Permanent damage is possible but usually occurs in only the most difficult cases. Depending on the branch of the nerve that is damaged you may experience: • Weakness of the lower lip, leading to a slightly crooked smile. Weakness of the eyelids, making it difficult to keep the eye closed.
Should a parotid tumor be removed?
Treatment Surgery is recommended for almost all parotid gland tumors, whether cancerous or benign. Although most tumors grow slowly and are non-cancerous, they will often continue to grow and occasionally can become cancerous. Treatment of a parotid tumor generally requires removing the parotid gland (parotidectomy).
How aggressive is clear cell carcinoma?
Clear cell carcinoma comprises a rare yet an aggressive subtype, accounting for less than 5% of all uterine carcinomas.
Is the parotid gland related to acinic cell carcinoma?
A gradual mass progression of the terminal end of the parotid gland usually affected. Almost 17 percent of the primary salivary gland carcinoma is related to the Acinic Cell Carcinoma.
How is ACC of the parotid gland treated?
Previous radiation exposure and familial predisposition are some of the risk factors for ACC. A slowly enlarging mass lesion in the tail of the parotid gland is the most frequent presentation. The diagnosis is usually confirmed with a fine needle aspiration biopsy, and surgical excision is the main treatment of this malignant neoplasm.
Where does acinic cell carcinoma occur in the salivary gland?
Acinic Cell Carcinoma is a low-grade neoplasm occurs on the epithelial cell lining of the salivary gland. A gradual mass progression of the terminal end of the parotid gland usually affected. Almost 17 percent of the primary salivary gland carcinoma is related to the Acinic Cell Carcinoma. The onset…
How is acinic cell carcinoma ( ACC ) treated?
Acinic cell carcinoma (ACC) is a rarest form of low-grade malignant salivary neoplasm in which the predominant site is the parotid gland and women are usually more frequently diagnosed than men. Surgical excision is the main treatment of this malignant neoplasm. Other treatment modalities such as radiotherapy may be indicated in some cases.