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What does thallium chloride do?

What does thallium chloride do?

Thallous chloride Tl 201 injection is used in adults to help diagnose heart disease (eg, coronary artery disease, heart attack). It is used in certain procedures called planar scintigraphy or single-photon emission computed tomography (SPECT).

How long should patients continue to exercise after injection of 201tl for stress MPI?

The protocol is to inject 111–148 MBq (3–4 mCi) of 201Tl intravenously at peak stress and to continue exercise for 1 min after injection.

What happens when Thallium 201 enters the body?

The radioactive isotope thallium 201 behaves physiologically as a potassium analog, and when injected intravenously accumulates rapidly within the cells of many organs. Uptake of the isotope reflects both regional perfusion and sodium-potassium pump activity.

What is a thallium 201 stress test?

This test is the same as a treadmill exercise test. This test checks the function of the heart during and after physical activity. In addition, an IV will be started and, at the peak of exercise, the patient will be injected with a mild isotope.

Why is Thallium-201 used in medicine?

Thallium-201 is a radiopharmaceutical agent used in the diagnosis of coronary artery disease and parathyroid hyperactivity. Other useful applications for a thallium-201 scan, like tumor diagnosis and olfacto-scintigraphy, are being explored and have shown promising results in various studies.

What is a bad TID ratio?

Results. The upper normal limits were 1.19 for TID and 1.23 for TIDed as established in 259 LLk patients. Both ratios increased with disease severity (P<. 0001). Incidence of abnormal TID increased from 2% in normal patients to > 36% in patients with severe CAD.

What is a normal summed stress score?

Summed stress scores of less than 3 are considered normal, whereas scores of 4–7, 8–12, and 13 or higher are indicative of low, intermediate, and high risk for a hard cardiac event.

How does thallium affect the human body?

Thallium can affect your nervous system, lung, heart, liver, and kidney if large amounts are eaten or drunk for short periods of time. Temporary hair loss, vomiting, and diarrhea can also occur and death may result after exposure to large amounts of thallium for short periods.

What is thallium used for medically?

How long does a thallium scan take?

The thallium stress test has two parts: at rest and while exercising. It takes about 4 hours to do both parts of the test. Thallium stress tests are done in a hospital, an imaging center, or a cardiologist’s clinic.

How do I prepare for a thallium stress test?

Wear comfortable clothes and shoes for exercising. Twenty-four hours before the test, you’ll need to avoid all caffeine, including tea, soda, coffee, chocolate — even decaffeinated coffee and drinks, which have small amounts of caffeine — and certain pain relievers.

Are there any risks of thallium stress test?

Risks and complications of a thallium stress test. Most people tolerate the thallium stress test very well. You may feel a sting as the medication that simulates exercise is injected, followed by a warm feeling. Some people may experience headache, nausea, and a racing heart .

What are the side effects of a thallium stress test?

Possible Side-effects of ThalliumStress Test. First and foremost, there is a dangerof the IV complications, namely including swelling, pain and bleeding inthe spot where the IV needle is positioned.

What does thallium do to people?

Studies in people who ingested large amounts of thallium over a short time have reported vomiting, diarrhea, temporary hair loss, and effects on the nervous system, lungs, heart, liver, and kidneys. It has caused death. It is not known what the effects are from ingesting low levels of thallium over a long time.

What is the definition of thallium exercise stress test?

What is a thallium stress test? A thallium stress test is a nuclear imaging test that shows how well blood flows into your heart while you’re exercising or at rest. This test is also called a cardiac or nuclear stress test.