How are oncology drugs named?
The ending letters (stem) of the generic names are like surnames that tell what family the drug is from and how the drug works to kill cancer cells. Monoclonal antibodies end with the stem “-mab” and small molecule inhibitors end with the stem “-ib”.
What is the suffix of the generic name of beta blockers?
A few examples of drug stems are: ▪ -olol: a suffix for beta blockers which include atenolol, bisoprolol, esmolol, metoprolol, and propranolol. These drugs share similar properties and treat conditions such as heart failure, cardiac arrhythmias and hypertension.
What drugs end in mab?
All MABs have names that include ‘mab’ at the end of their generic name, for example:
- trastuzumab (Herceptin)
- pertuzumab (Perjeta)
- bevacizumab (Avastin)
- rituximab (Mabthera)
What suffix is found at the end of many antihistamine names?
Antihistamines are given to treat allergy symptoms, such as sneezing, runny nose, itching, or hives, and include drugs ending in -ine, such as diphenhydramine, loratadine, and brompheniramine.
What does NIB mean in drugs?
The suffix “nib” indicates a small-molecule inhibitor (“nib” is verbal shorthand for “inhibit”) of kinase enzymes. More specifically, “tinib” is used for tyrosine kinase inhibitors, “anib” for angiogenesis inhibitors, and rafenib for rapidly accelerated fibrosarcoma (RAF) kinase inhibitors.
What is another name for dapsone?
Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.
Why do Biologics end in mab?
“xi” means the antibody is chimeric, which means it is about two-thirds human, one-third mouse, and. “mab” denotes the class of drug – a monoclonal antibody.
Why do drug names end in mab?
The suffix “-mab” is used for monoclonal antibodies, antibody fragments and radiolabeled antibodies. For polyclonal mixtures of antibodies, “-pab” is used. The -pab suffix applies to polyclonal pools of recombinant monoclonal antibodies, as opposed to polyclonal antibody preparations isolated from blood.
What medications end in the suffix sartan?
Angiotensin receptor blockers are a class of medicines that is used to treat high blood pressure (also known as hypertension). These medicines have names that end in ‘sartan’, including valsartan, irbesartan, candesartan, losartan and olmesartan.
Which drug class has the suffix Olone?
These drug prefixes, roots, and suffixes apply only to generic names.
| prefix, root, suffix | examples (generic names) |
|---|---|
| -olol | atenolol; metoprolol; nadolol; pindolol; propranolol; timolol |
| -olone | fluocinolone; fluorometholone; prednisolone; triamcinolone |
| -olone | nandrolone; oxandrolone; oxymetholone |
What’s the difference between tinib, ANIB, and nib?
The suffix “nib” indicates a small-molecule inhibitor (“nib” is verbal shorthand for “inhibit”) of kinase enzymes. More specifically, “tinib” is used for tyrosine kinase inhibitors, “anib” for angiogenesis inhibitors, and rafenib for rapidly accelerated fibrosarcoma (RAF) kinase inhibitors.
What does the suffix nib stand for in drug names?
The suffix “nib” indicates a small-molecule inhibitor (“nib” is verbal shorthand for “inhibit”) of kinase enzymes. More specifically, “tinib” is used for tyrosine kinase inhibitors, “anib” for angiogenesis inhibitors, and rafenib for rapidly accelerated fibrosarcoma (RAF) kinase inhibitors. [ 8]
What does it mean when someone says ” tinib “?
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What does zomib stand for in medical category?
The ‘Mibs’ The suffix “zomib” is the designation for protease or proteasome inhibitors. Mibs are small molecules that work inside cancer cells to slow proliferation and increase apoptosis (cell death). In 2015, the FDA approved ixazomib (Ninlaro®; Takeda Oncology) for multiple myeloma.